Arthroscopy: The Journal of Arthroscopic and Related Surgery
Volume 25, Issue 7 , Pages 707-715, July 2009

Local Anesthetics Induce Chondrocyte Death in Bovine Articular Cartilage Disks in a Dose- and Duration-Dependent Manner

  • Ian K.Y. Lo, M.D., F.R.C.S.C.

      Affiliations

    • Department of Surgery, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    • Corresponding Author InformationAddress correspondence and reprint requests to Ian K. Y. Lo, M.D., F.R.C.S.C., Department of Surgery, University of Calgary, 3330 Hospital Dr NW, Calgary, Alberta, Canada
    • ,
  • Paul Sciore, Ph.D.

      Affiliations

    • Department of Surgery, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    • ,
  • May Chung, B.Sc.

      Affiliations

    • Department of Surgery, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    • ,
  • Sherri Liang, B.Sc.

      Affiliations

    • Department of Surgery, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    • ,
  • Richard B. Boorman, M.D., F.R.C.S.C.

      Affiliations

    • Department of Surgery, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    • ,
  • Gail M. Thornton, Ph.D.

      Affiliations

    • Department of Surgery, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    • ,
  • Jerome B. Rattner, Ph.D.

      Affiliations

    • Department of Anatomy and Cell Biology, University of Calgary, Calgary, Alberta, Canada
    • ,
  • Kenneth Muldrew, Ph.D.

      Affiliations

    • Department of Anatomy and Cell Biology, University of Calgary, Calgary, Alberta, Canada

Received 20 November 2008; accepted 30 March 2009.

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 Supported by the Canadian Institutes of Health Research. The authors report no conflict of interest.

PII: S0749-8063(09)00341-7

doi:10.1016/j.arthro.2009.03.019

Arthroscopy: The Journal of Arthroscopic and Related Surgery
Volume 25, Issue 7 , Pages 707-715, July 2009

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