Arthroscopy: The Journal of Arthroscopic and Related Surgery
Volume 25, Issue 12 , Pages 1380-1386 , December 2009

Apoptotic Pathways in Degenerative Disk Lesions in the Wrist

  • Frank Unglaub, M.D.

      Affiliations

    • Department of Plastic and Hand Surgery, University of Erlangen, Erlangen, Germany
    • Corresponding Author InformationAddress correspondence and reprint requests to Frank Unglaub, M.D., Department of Plastic and Hand Surgery, University of Erlangen, Krankenhausstrasse 12, 91054 Erlangen, Germany
    • ,
  • Susanne B. Thomas, B.S.

      Affiliations

    • Department of Plastic and Hand Surgery, University of Erlangen, Erlangen, Germany
    • ,
  • Markus W. Kroeber, M.D.

      Affiliations

    • Department of Orthopaedic Surgery, Kantonsspital, Saint Gallen, Switzerland
    • ,
  • Adrian Dragu, M.D.

      Affiliations

    • Department of Plastic and Hand Surgery, University of Erlangen, Erlangen, Germany
    • ,
  • Jörg Fellenberg, Ph.D.

      Affiliations

    • Division of Experimental Orthopaedics, Orthopaedic University Hospital, Heidelberg, Germany
    • ,
  • Maya B. Wolf, B.S.

      Affiliations

    • Department of Plastic and Hand Surgery, University of Erlangen, Erlangen, Germany
    • ,
  • Raymund E. Horch, M.D.

      Affiliations

    • Department of Plastic and Hand Surgery, University of Erlangen, Erlangen, Germany

Received 11 September 2008 ,Accepted 17 April 2009.

References 

  1. Palmer AK. Triangular fibrocartilage complex lesions: A classification. J Hand Surg [Am]. 1989;14:594–606
  2. Friedman SL, Palmer AK. The ulnar impaction syndrome. Hand Clin. 1991;7:295–310
  3. Palmer AK, Werner FW. The triangular fibrocartilage complex of the wrist—Anatomy and function. J Hand Surg [Am]. 1981;6:153–162
  4. Mikic ZD. Detailed anatomy of the articular disc of the distal radioulnar joint. Clin Orthop Relat Res. 1989;123–132
  5. Unglaub F, Fellenberg J, Germann G, Bickert B, Sauerbier M, Richter W. Detection of apoptotic cartilage cells in symptomatic central tears of the triangular fibrocartilage. J Hand Surg [Am]. 2007;32:618–622
  6. Unglaub F, Wolf MB, Thome MA, Germann G, Sauerbier M, Reiter A. Correlation of ulnar length and apoptotic cell death in degenerative lesions of the triangular fibrocartilage. Arthroscopy. 2008;24:299–304
  7. Chen B, Fellenberg J, Wang H, Carstens C, Richter W. Occurrence and regional distribution of apoptosis in scoliotic discs. Spine. 2005;30:519–524
  8. Park JB, Lee JK, Park SJ, Kim KW, Riew KD. Mitochondrial involvement in fas-mediated apoptosis of human lumbar disc cells. J Bone Joint Surg Am. 2005;87:1338–1342
  9. Bernstein MA, Nagle DJ, Martinez A, Stogin JM, Wiedrich TA. A comparison of combined arthroscopic triangular fibrocartilage complex debridement and arthroscopic wafer distal ulna resection versus arthroscopic triangular fibrocartilage complex debridement and ulnar shortening osteotomy for ulnocarpal abutment syndrome. Arthroscopy. 2004;20:392–401
  10. Osterman AL, Terrill RG. Arthroscopic treatment of TFCC lesions. Hand Clin. 1991;7:277–281
  11. Husby T, Haugstvedt JR. Long-term results after arthroscopic resection of lesions of the triangular fibrocartilage complex. Scand J Plast Reconstr Surg Hand Surg. 2001;35:79–83
  12. Chloros GD, Wiesler ER, Poehling GG. Current concepts in wrist arthroscopy. Arthroscopy. 2008;24:343–354
  13. Estrella EP, Hung LK, Ho PC, Tse WL. Arthroscopic repair of triangular fibrocartilage complex tears. Arthroscopy. 2007;23:729–737.e1Available online at www.arthroscopyjournal.org
  14. Bain GI, Munt J, Turner PC. New advances in wrist arthroscopy. Arthroscopy. 2008;24:355–367
  15. Pederzini LA, Tosi M, Prandini M, Botticella C. All-inside suture technique for Palmer class 1B triangular fibrocartilage repair. Arthroscopy. 2007;23:1130.e1–1130.e4Available online at www.arthroscopyjournal.org
  16. Chen AC, Hsu KY, Chang CH, Chan YS. Arthroscopic suture repair of peripheral tears of triangular fibrocartilage complex using a volar portal. Arthroscopy. 2005;21:1406.e1–1406.e4Available online at www.arthroscopyjournal.org
  17. de Araujo W, Poehling GG, Kuzma GR. New Tuohy needle technique for triangular fibrocartilage complex repair: Preliminary studies. Arthroscopy. 1996;12:699–703
  18. Reiter AW, Wolf MB, Schmid U, et al. Arthroscopic repair of Palmer 1b triangular fibrocartilage complex tears. Arthroscopy. 2008;24:1244–1250
  19. Unglaub F, Kroeber MW, Thomas SB, et al. Incidence and distribution of blood vessels in punch biopsies of Palmer 1A disc lesions in the wrist. Arch Orthop Trauma Surg. 2009;129:631–634
  20. Unglaub F, Hahn P, Wolf E, Germann G, Bickert B, Sauerbier M. Degeneration process of symptomatic central tears in the triangular fibrocartilage. Ann Plast Surg. 2007;59:515–519
  21. Milz S, Sicking B, Sprecher CM, Putz R, Benjamin M. An immunohistochemical study of the triangular fibrocartilage complex of the wrist: Regional variations in cartilage phenotype. J Anat. 2007;211:1–7
  22. Lavrik IN, Golks A, Krammer PH. Caspases: Pharmacological manipulation of cell death. J Clin Invest. 2005;115:2665–2672
  23. Tay SC, Tomita K, Berger RA. The “ulnar fovea sign” for defining ulnar wrist pain: An analysis of sensitivity and specificity. J Hand Surg [Am]. 2007;32:438–444
  24. Green DR, Kroemer G. Pharmacological manipulation of cell death: Clinical applications in sight?. J Clin Invest. 2005;115:2610–2617
  25. Bilsland J, Harper S. Caspases and neuroprotection. Curr Opin Investig Drugs. 2002;3:1745–1752
  26. Gagarina V, Carlberg AL, Pereira-Mouries L, Hall DJ. Cartilage oligomeric matrix protein protects cells against death by elevating members of the IAP family of survival proteins. J Biol Chem. 2008;283:648–659
  27. Huser CA, Peacock M, Davies ME. Inhibition of caspase-9 reduces chondrocyte apoptosis and proteoglycan loss following mechanical trauma. Osteoarthritis Cartilage. 2006;14:1002–1010
  28. Creagh EM, Conroy H, Martin SJ. Caspase-activation pathways in apoptosis and immunity. Immunol Rev. 2003;193:10–21
  29. Scaffidi C, Fulda S, Srinivasan A, et al. Two CD95 (APO-1/Fas) signaling pathways. Embo J. 1998;17:1675–1687

 Supported by the ELAN Fonds, University of Erlangen, Erlangen, Germany. The authors report no conflict of interest.

PII: S0749-8063(09)00420-4

doi: 10.1016/j.arthro.2009.04.071

Arthroscopy: The Journal of Arthroscopic and Related Surgery
Volume 25, Issue 12 , Pages 1380-1386 , December 2009

Article Tools

* Image Usage & Resolution