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The diagnosis and management of osteochondral lesions of the talus: osteochondral allograft update

      The management of osteochondral defects of the talus remains a clinical challenge as a result of the poor intrinsic healing potential of cartilage. Osteochondral lesions of the talus (OLT) is a relatively commonly cause of ankle pain and disability (Fig 1). Cartilage has very limited ability for repair or regeneration. A biologic solution to the repair of significant cartilage defects is the “holy grail.” Some of the obstacles to cartilage repair are the fact that it is highly vascular, hypocellular, and the chondrocytes are “imprisoned” in a matrix (Fig 2).
      Figure thumbnail GR1
      Figure 1Magnetic resonance image of osteochondral lesions of the talus at the posteromedial talar dome.
      Figure thumbnail GR2
      Figure 2Cross-section of articular cartilage shows chondrocytes imbedded in matrix.
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