Purpose: The incidence and progression of osteoarthritis over a time period of 35 years following
anterior cruciate ligament (ACL) disruption in high-level athletes has not been clearly
determined. Our study examined this. Type of Study: Retrospective cohort clinical study. Methods: Following a central guideline, between March 1963 and December 1965, all 19 athletes
in the Olympic program of former East Germany who sustained an ACL injury were treated
without reconstruction. In a retrospective cohort study, the clinical results were
evaluated for all patients from 1975 and 1985 and for 17 of the 19 patients in 2000;
18 of the 19 patients were examined arthroscopically in 1985. Results: All patients were able to return to sports after a period of 6 to 14 weeks. Ten years
after the injury, meniscectomy had to be performed in 15 of the 19 patients (79%).
The medial meniscus was affected in 13 patients (68%) and the lateral in 7 (37%);
20 years after the injury, meniscectomy was necessary in 18 of the 19 patients (95%).
In 1985, in 18 of the 19 knees, arthroscopy was performed and 13 patients (68%) had
a grade 4 chondral lesion. Ten total knee replacements had to be performed until the
end of the year 2000. Conclusions: We conclude that, despite the possibility of return to high-level activity with a
definitive unstable knee, this will lead in 95% of cases to meniscal and cartilage
damage over the next 20 years. In addition, cartilage damage and progressive osteoarthritis
will occur and patients will have a high risk of becoming a candidate for further
total joint replacement. Level of Evidence: Level IV.
Key Words
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© 2005 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.