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Summary
Eighteen adult rabbits with mechanically induced degenerative arthritis of one knee
were divided into two groups. The first group underwent arthrotomy and lavage of the
arthritic joint. The second group underwent arthrotomy and irradiation of the degenerate
articular surface with the Excimer (xenon chloride ultraviolet, 308-nm) laser (Arthrex
Arthrolase MAX-10, Germany) in a saline environment. Rabbits from each group were
killed at intervals up to 12 weeks for histological and metabolic studies of their
articular cartilage. In the control group there was no improvement in the macroscopic
or microscopic appearance of the articular surface. In the laser-irradiated group
initially there was macroscopic and microscopic smoothing of the fibrillated surface.
By 6 weeks the surface had begun to show the reappearance of fibrillation. There was
no evidence that there was any increase or decrease in mitotic or metabolic activity
in the laser-irradiated group as compared with the controls.
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References
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Article Info
Footnotes
*Financial support for this project was provided by The Orthopaedic and Arthritic Hospital, Toronto, Canada, and The Jensa Research Corporation.
Identification
Copyright
© 1994 Arthroscopy Association of North America. All rights reserved. Published by Elsevier Inc.
