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Case Report| Volume 23, ISSUE 4, P447.e1-447.e4, April 2007

Non-Hodgkin’s Lymphoma of the Knee Diagnosed by Arthroscopy

Published:October 18, 2006DOI:https://doi.org/10.1016/j.arthro.2006.01.016

      Abstract

      We report a case of non-Hodgkin’s lymphoma of the knee diagnosed by arthroscopy in an otherwise healthy, active 31-year-old woman. Plain radiographs were unremarkable and magnetic resonance imaging findings indicated the presence of a posterior horn medial meniscal tear. The patient underwent arthroscopy for a planned partial medial meniscectomy. However, on joint visualization, hyperemic hypertrophic synovitis was found. Tissue samples were collected and sent for histopathologic testing that revealed diffuse large B cells. The patient was referred to the oncology department where 2 lesions on her lung were also found. Malignant disease should be in the mindset of the orthopaedic surgeon when a patient presents with constant pain, an unusual history, atypical response to conventional treatment, or a diagnostic dilemma.

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      References

        • Dorfman H.D.
        • Siegal H.L.
        • Perry M.C.
        Non-Hodgkin’s lymphoma of the synovium simulating rheumatoid arthritis.
        Arthritis Rheum. 1987; 30: 155-161
        • Schmidt A.G.
        • Kohn D.
        • Bernards J.
        Solitary skeletal lesions as primary manifestations of non-Hodgkin’s lymphoma.
        Arch Orthop Trauma Surg. 1994; 113: 121-128
        • Bagga S.
        • Gupta S.M.
        • Johns W.
        Scintigraphic detection of a disseminated synovial lymphoma in a postrenal transplant patient.
        Clin Nucl Med. 1996; 21: 615-618
        • Haase K.K.
        • Durk H.
        • Baumbach A.
        Non-Hodgkin’s lymphoma presenting as knee monoarthritis with a popliteal cyst.
        J Rheumatol. 1990; 17 (letter): 1252-1254
        • Calabro J.J.
        Cancer and arthritis.
        Arthritis Rheum. 1967; 10: 553-567
        • Pear B.L.
        Skeletal manifestations of the lymphomas and leukemias.
        Semin Roentgenol. 1974; 9: 229-240
        • Vieta J.O.
        • Friedell H.L.
        • Craver L.F.
        A survey of Hodgkin’s disease and lymphosarcoma of bone.
        Radiology. 1942; 39: 1-15
        • Rosenberg S.A.
        • Diamond J.D.
        • Jaslowitz B.
        Lymphosarcoma: A review of 1269 cases.
        Medicine (Baltimore). 1961; 40: 31-84
        • Gaudin P.
        • Juvin R.
        • Rozand Y.
        Skeletal involvement as the initial disease manifestation in Hodgkin’s disease: A review of 6 cases.
        J Rheumatol. 1992; 19: 146-152
        • Caldwell D.S.
        • McMallum R.M.
        Rheumatologic manifestations of cancer.
        Med Clin North Am. 1986; 70: 385-417
        • Martin V.M.
        • Bennett R.M.
        • Hughes G.R.V.
        Lymphosarcomatous arthropathy.
        Ann Rheum Dis. 1973; 32: 162-166
        • Newton P.
        • Freemont A.T.
        • Noble J.
        Secondary malignant synovitis: Report of three cases and review of the literature.
        Q J Med. 1984; 209: 135-143
        • Tiwari I.
        • Thomas D.R.
        • Pathy M.S.
        Non-Hodgkin’s lymphoma presenting in synovial membrane.
        Br J Clin Pract. 1982; 36: 327-328
        • Barton A.
        • Hickling P.
        Synovial involvement in Hodgkin’s disease.
        Br J Rheumatol. 1986; 25: 391-392
        • Keller M.S.
        • Jackson D.P.
        • Breslow A.
        Chronic knee pain in a 35-year-old man.
        Invest Radiol. 1981; 16: 1-6
        • Thompson K.S.
        • Reyes C.V.
        • Jensen J.
        Synovial metastasis: Diagnosis by fine-needle aspiration cytologic investigation.
        Diagn Cytopathol. 1996; 15: 334-337
        • Rice D.M.
        • Semble E.
        • Ahl E.T.
        Primary lymphoma of bone presenting as monoarthritis.
        J Rheumatol. 1984; 11: 851-854
        • Mariette X.
        • de Roquancourt A.
        • d’Agay M.F.
        Monoarthritis revealing non-Hodgkin’s T cell lymphoma of the synovium.
        Arthritis Rheum. 1988; 31 (letter): 571-572
        • Adunsky A.
        • Yaretzky A.
        • Klajman A.
        Malignant lymphoma presenting as sternoclavicular joint arthritis.
        Arthritis Rheum. 1980; 23: 1331-1332
        • Mody G.M.
        • Cassim B.
        Rheumatologic manifestations of malignancy.
        Curr Opin Rheumatol. 1997; 9: 75-79
        • Emkey R.D.
        • Ragsdale B.D.
        • Ropes M.W.
        • et al.
        A case of lymphoproliferative disease presenting as juvenile rheumatoid arthritis.
        Am J Med. 1973; 54: 825-828