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- Developments in the clinical understanding of osteoarthritis.Arthritis Res Ther. 2009; 11: 203
- Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritis.Trends Mol Med. 2012; 18: 109-118
- Etiology of osteoarthritis: Genetics and synovial joint development.Nat Rev Rheumatol. 2012; 8: 77-89
- The effect of osteoarthritis definition on prevalence and incidence estimates: A systematic review.Osteoarthritis Cartilage. 2011; 19: 1270-1285
- Cost-effectiveness analyses of osteoarthritis oral therapies: A systematic review.Appl Health Econ Health Policy. 2013; 11: 593-618
- Health economics in the field of osteoarthritis: An expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO).Semin Arthritis Rheum. 2013; 43: 303-313
Filardo G, Kon E, Roffi A, Di Matteo B, Merli ML, Marcacci M. Platelet-rich plasma: Why intra-articular? A systematic review of preclinical studies and clinical evidence on PRP for joint degeneration. Knee Surg Sports Traumatol Arthrosc in press, available online 26 November, 2013. http//dx.doi.org/10.1007/s00167-013-2743-1.
- Platelet-rich plasma in the pathologic processes of cartilage: Review of basic science evidence.Arthroscopy. 2013; 29: 1399-1409
- Basic science and clinical application of platelet-rich plasma for cartilage defects and osteoarthritis: A review.Osteoarthritis Cartilage. 2013; 21: 1627-1637
- A biological therapy to osteoarthritis treatment using platelet-rich plasma.Expert Opin Biol Ther. 2013; 13: 1161-1172
- Platelet-rich plasma: Preparation and formulation.Oper Tech Orthop. 2012; 22: 25-32
- Classification of platelet concentrates: From pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF).Trends Biotechnol. 2009; 27: 158-167
- Sports medicine applications of platelet rich plasma.Curr Pharm Biotechnol. 2012; 13: 1185-1195
- Platelet-rich plasma: The PAW classification system.Arthroscopy. 2012; 28: 998-1009
- The role of platelet-rich plasma in arthroscopic rotator cuff repair: A systematic review with quantitative synthesis.Arthroscopy. 2012; 28: 1718-1727
- Efficacy of autologous platelet-rich plasma use for orthopaedic indications: A meta-analysis.J Bone Joint Surg Am. 2012; 94: 298-307
- The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: Explanation and elaboration.BMJ. 2009; 339: b2700
- Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement.PLoS Med. 2009; 6: e1000097
- Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association.Arthritis Rheum. 1986; 29: 1039-1049
- The Cochrane Collaboration's tool for assessing risk of bias in randomised trials.BMJ. 2011; 343: d5928
- Grading quality of evidence and strength of recommendations.BMJ. 2004; 328: 1490
- GRADE: An emerging consensus on rating quality of evidence and strength of recommendations.BMJ. 2008; 336: 924-926
- Platelet-rich plasma (PRP) injections as an effective treatment for early osteoarthritis.Eur J Orthop Surg Traumatol. 2013; 23: 573-580
- Comparison between hyaluronic acid and platelet-rich plasma, intra-articular infiltration in the treatment of gonarthrosis.Am J Sports Med. 2012; 40: 2822-2827
- Platelet-rich plasma vs hyaluronic acid to treat knee degenerative pathology: Study design and preliminary results of a randomized controlled trial.BMC Musculoskelet Disord. 2012; 13: 229
- Intraarticular application of autologous conditioned serum (ACS) reduces bone tunnel widening after ACL reconstructive surgery in a randomized controlled trial.Knee Surg Sports Traumatol Arthrosc. 2011; 19: S36-S46
- Platelet-rich plasma: Intra-articular knee injections produced favorable results on degenerative cartilage lesions.Knee Surg Sports Traumatol Arthrosc. 2010; 18: 472-479
- Platelet-rich plasma treatment in symptomatic patients with knee osteoarthritis: Preliminary results in a group of active patients.Sports Health. 2012; 4: 162-172
- Platelet-rich plasma intra-articular injection versus hyaluronic acid viscosupplementation as treatments for cartilage pathology: From early degeneration to osteoarthritis.Arthroscopy. 2011; 27: 1490-1501
- Injection of platelet-rich plasma in patients with primary and secondary knee osteoarthritis: A pilot study.Am J Phys Med Rehabil. 2010; 89: 961-969
- Treatment with platelet-rich plasma is more effective than placebo for knee osteoarthritis: A prospective, double-blind, randomized trial.Am J Sports Med. 2013; 41: 356-364
- Treatment of knee joint osteoarthritis with autologous platelet-rich plasma in comparison with hyaluronic acid.Am J Phys Med Rehabil. 2012; 91: 411-417
- Infiltration of plasma rich in growth factors for osteoarthritis of the knee short-term effects on function and quality of life.Arch Orthop Trauma Surg. 2011; 131: 311-317
- Platelet-rich plasma intra-articular injections for cartilage degeneration and osteoarthritis: Single- versus double-spinning approach.Knee Surg Sports Traumatol Arthrosc. 2012; 20: 2082-2091
- Intra-articular injection of an autologous preparation rich in growth factors for the treatment of knee OA: A retrospective cohort study.Clin Exp Rheumatol. 2008; 26: 910-913
- A randomized clinical trial evaluating plasma rich in growth factors (PRGF-Endoret) versus hyaluronic acid in the short-term treatment of symptomatic knee osteoarthritis.Arthroscopy. 2012; 28: 1070-1078
- Platelet-rich plasma injection is more effective than hyaluronic acid in the treatment of knee osteoarthritis.Acta Chir Orthop Traumatol Cech. 2013; 80: 278-283
- Comparison of intra-articular injections of plasma rich in growth factors (PRGF-Endoret) versus Durolane hyaluronic acid in the treatment of patients with symptomatic osteoarthritis: A randomized controlled trial.Arthroscopy. 2013; 29: 1635-1643
- The efficacy of platelet-rich plasma in the treatment of symptomatic knee osteoarthritis: A systematic review with quantitative synthesis.Arthroscopy. 2013; 29: 2037-2048
- Comparative effectiveness of platelet-rich plasma injections for treating knee joint cartilage degenerative pathology: A systematic review and meta-analysis.Arch Phys Med Rehabil. 2014; 95: 562-575
- Platelet-rich plasma in the management of articular cartilage pathology: A systematic review.Clin J Sport Med. 2014; 24: 31-43
- Efficacy and safety of corticosteroid injections and other injections for management of tendinopathy: A systematic review of randomised controlled trials.Lancet. 2010; 376: 1751-1767
- Autologous growth factor injections in chronic tendinopathy: A systematic review.Br Med Bull. 2010; 95: 63-77
- A systematic review of the use of platelet-rich plasma in sports medicine as a new treatment for tendon and ligament injuries.Clin J Sport Med. 2011; 21: 344-352
- The effect of platelet concentrates on graft maturation and graft-bone interface healing in anterior cruciate ligament reconstruction in human patients: A systematic review of controlled trials.Arthroscopy. 2011; 27: 1573-1583
- The effect of platelet-rich plasma on clinical outcomes in lateral epicondylitis.Arthroscopy. 2013; 29: 1851-1862
- Strong evidence against platelet-rich plasma injections for chronic lateral epicondylar tendinopathy: A systematic review.Br J Sports Med. 2014; 48: 952-956
- Mohamed Ali MR. Platelet-rich plasma (PRP) for acute muscle injury: A systematic review.PLoS One. 2014; 9: e90538
- Platelet-rich plasma for foot and ankle pathologies: A systematic review.Foot Ankle Surg. 2014; 20: 2-9
Anitua E, Sánchez M, Prado R, Orive G. The type of platelet-rich plasma may influence the safety of the approach. Knee Surg Sports Traumatol Arthrosc in press, available online 9 May, 2012. http://dx.doi.org/10.1007/s00167-012-2043-1.
- Optimization of leukocyte concentration in platelet-rich plasma for the treatment of tendinopathy.J Bone Joint Surg Am. 2012; 94: e1431-e1438
- Growth factor and catabolic cytokine concentrations are influenced by the cellular composition of platelet-rich plasma.Am J Sports Med. 2011; 39: 2135-2140
- Platelet-rich plasma for managing pain and inflammation in osteoarthritis.Nat Rev Rheumatol. 2013; 9: 721-730
- Platelet-rich plasma exerts antinociceptive activity by a peripheral endocannabinoid-related mechanism.Tissue Eng Part A. 2013; 19: 2120-2129
- Knee osteoarthritis: Hyaluronic acid, platelet-rich plasma or both in association?.Expert Opin Biol Ther. 2014; 14: 635-649
- Therapeutic trajectory following intra-articular hyaluronic acid injection in knee osteoarthritis—Meta-analysis.Osteoarthritis Cartilage. 2011; 19: 611-619
- Viscosupplementation for the treatment of osteoarthritis of the knee.Cochrane Database Syst Rev. 2006; : CD005321
- Platelet-rich plasma intra-articular knee injections for the treatment of degenerative cartilage lesions and osteoarthritis.Knee Surg Sports Traumatol Arthrosc. 2011; 19: 528-535
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The authors report that they have no conflicts of interest in the authorship and publication of this article.