Abstract
In contrast to the AAOS knee osteoarthritis guidelines, systematic review of overlapping meta-analyses shows that viscosupplementation with intra-articular hyaluronic acid injection reduces knee osteoarthritis pain and improves function according to the highest level of evidence.
Campbell, Erickson, Saltzman, Mascarenhas, Bach, Cole, and Verma, from Rush University Medical Center present, “Is local viscosupplementation injection clinically superior to other therapies in the treatment of osteoarthritis of the knee? A systematic review of overlapping meta-analyses.”
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As usual, the team from Rush is uber relevant because, “Knee pain secondary to osteoarthritis (OA) is one of the most common complaints in patients presenting to orthopaedic clinics.”- Campbell K.A.
- Erickson B.J.
- Saltzman B.M.
- Mascarenhas R.
- Bach Jr., B.R.
- Cole B.J.
- Verma N.N.
Is local viscosupplementation injection clinically superior to other therapies in the treatment of osteoarthritis of the knee? A systematic review of overlapping meta-analyses.
Arthroscopy. 2015; 31: 2036-2045
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Campbell et al. are also unafraid of controversy, considering that viscosupplementation, also known as hyaluronic acid (HA), has been much maligned by the American Academy of Orthopaedic Surgeons.- Campbell K.A.
- Erickson B.J.
- Saltzman B.M.
- Mascarenhas R.
- Bach Jr., B.R.
- Cole B.J.
- Verma N.N.
Is local viscosupplementation injection clinically superior to other therapies in the treatment of osteoarthritis of the knee? A systematic review of overlapping meta-analyses.
Arthroscopy. 2015; 31: 2036-2045
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In contrast to the AAOS Clinical Practice Guidelines,
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Campbell et al. well demonstrate that viscosupplementation with intra-articular HA injection reduces knee osteoarthritis pain and improves function according to the highest level of evidence meta-analyses.References
- Is local viscosupplementation injection clinically superior to other therapies in the treatment of osteoarthritis of the knee? A systematic review of overlapping meta-analyses.Arthroscopy. 2015; 31: 2036-2045
- The American Academy of Orthopaedic Surgeons evidence-based guideline on treatment of osteoarthritis of the knee, 2nd edition.J Bone Joint Surg Am. 2013; 95: 1885-1886
- Did the American Academy of Orthopaedic Surgeons osteoarthritis guidelines miss the mark?.Arthroscopy. 2014; 30: 86-89
- AAOS osteoarthritis guideline: Transparency and credibility.Arthroscopy. 2014; 30: 656-658
- Authors’ reply.Arthroscopy. 2014; 30: 658-659
- An epidemiologic analysis of clinical practice guidelines for non-arthroplasty treatment of osteoarthritis of the knee.Arthroscopy. 2014; 30: 65-71
- Congratulations and condemnations: Level I evidence prize for femoral tunnel position in ACL reconstruction, and AAOS Clinical Practice Guidelines miss the mark—Again.Arthroscopy. 2014; 30: 2-5
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See related article on page 2036
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© 2015 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.
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- Is Local Viscosupplementation Injection Clinically Superior to Other Therapies in the Treatment of Osteoarthritis of the Knee: A Systematic Review of Overlapping Meta-analysesArthroscopyVol. 31Issue 10
- PreviewTo conduct a systematic review of overlapping meta-analyses comparing treatment of knee osteoarthritis (OA) with intra-articular viscosupplementation (intra-articular hyaluronic acid [IA-HA]) versus oral nonsteroidal anti-inflammatory drugs (NSAIDs), intra-articular corticosteroids (IA-corticosteroids), intra-articular platelet-rich plasma (IA-PRP), or intra-articular placebo (IA-placebo) to determine which meta-analyses provide the best current evidence and identify potential causes of discordance.
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